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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGK2
All Species:
9.09
Human Site:
S74
Identified Species:
16.67
UniProt:
Q9HBY8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBY8
NP_057360.2
427
47604
S74
G
T
P
S
P
Q
P
S
R
A
N
G
N
I
N
Chimpanzee
Pan troglodytes
XP_001142856
441
49512
S88
G
S
P
S
P
Q
P
S
R
A
N
G
N
I
N
Rhesus Macaque
Macaca mulatta
XP_001083986
450
50817
S97
G
T
T
S
P
Q
P
S
K
A
N
G
N
I
N
Dog
Lupus familis
XP_849801
431
48950
P77
N
A
N
P
S
P
P
P
S
P
S
Q
Q
I
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZS5
367
41341
R31
P
S
A
N
P
N
A
R
P
T
D
F
D
F
L
Rat
Rattus norvegicus
Q8R4U9
367
41343
R31
P
S
A
N
P
N
A
R
P
T
D
F
D
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511204
429
48309
S67
L
G
N
P
Q
P
S
S
P
N
G
N
I
N
L
Chicken
Gallus gallus
Q6U1I9
432
48872
P78
N
A
N
P
S
P
P
P
S
P
S
Q
Q
I
N
Frog
Xenopus laevis
Q6GLY8
434
49082
P80
N
E
N
S
S
P
P
P
S
H
S
Q
Q
I
N
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
P79
N
S
N
P
S
P
P
P
S
P
S
Q
Q
I
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8INB9
611
68466
Q245
A
E
D
E
L
S
E
Q
F
S
V
Q
G
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q2PJ68
463
54273
D114
F
F
H
L
E
S
P
D
D
D
E
N
N
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P12688
680
76461
G326
I
T
L
D
N
G
L
G
K
I
N
I
S
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
83.5
62.4
N.A.
81
80.5
N.A.
73.6
62
60.3
63.5
N.A.
33.8
N.A.
41.9
N.A.
Protein Similarity:
100
87.7
86.2
75.8
N.A.
83.6
83.3
N.A.
80.8
75.4
74.8
74.3
N.A.
45.3
N.A.
58.5
N.A.
P-Site Identity:
100
93.3
86.6
20
N.A.
6.6
6.6
N.A.
6.6
20
26.6
20
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
33.3
33.3
N.A.
6.6
26.6
33.3
33.3
N.A.
6.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
16
0
0
0
16
0
0
24
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
0
8
8
8
16
0
16
0
16
% D
% Glu:
0
16
0
8
8
0
8
0
0
0
8
0
0
0
0
% E
% Phe:
8
8
0
0
0
0
0
0
8
0
0
16
0
16
0
% F
% Gly:
24
8
0
0
0
8
0
8
0
0
8
24
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
8
8
62
0
% I
% Lys:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% K
% Leu:
8
0
8
8
8
0
8
0
0
0
0
0
0
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
31
0
39
16
8
16
0
0
0
8
31
16
31
8
54
% N
% Pro:
16
0
16
31
39
39
62
31
24
24
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
24
0
8
0
0
0
39
31
0
0
% Q
% Arg:
0
0
0
0
0
0
0
16
16
0
0
0
0
0
0
% R
% Ser:
0
31
0
31
31
16
8
31
31
8
31
0
8
0
0
% S
% Thr:
0
24
8
0
0
0
0
0
0
16
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _